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Defactinib hydrochloride is the hydrochloride salt of defactinib, a small-molecule focal adhesion kinase (FAK) inhibitor. It inhibits FAK phosphorylation at Tyr397 in a time- and dose-dependent manner and is used in preclinical research to study tumor biology and signaling pathways.
Inhibits FAK phosphorylation at Tyr397 in a time- and dose-dependent manner.
Hydrochloride salt supplied as a white to off-white solid.
High chemical purity suitable for biochemical and cellular assays.
Available in multiple solid sizes and DMSO stock solutions for flexible dosing.
Used for research into cancer signaling and pharmacology applications.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Yonkenafil hydrochloride is the hydrochloride salt of a selective phosphodiesterase 5 (PDE5) inhibitor supplied for research use. It is provided as a high-purity solid suitable for in vitro and preclinical studies involving PDE5-related pathways, neuroscience, and pharmacology. Typical solvent compatibility includes DMSO; follow the SDS and laboratory safety procedures.
High purity suitable for research.
Solid form for accurate weighing and formulation.
Soluble in DMSO for assay preparation.
Appropriate for in vitro and preclinical pharmacology studies.
Available in small-scale vials for dose-ranging experiments.
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TPPB is a benzolactam-derived, cell-permeable protein kinase C (PKC) activator used in biochemical and cell-based research. It exhibits high affinity for PKC with a reported Ki of 11.9 nM and is applied in studies of cell differentiation and amyloid precursor protein modulation. This compound is intended for research use only and should be handled according to safety data guidelines.
High-affinity PKC activation (Ki = 11.9 nM).
Cell-permeable small molecule suitable for cellular assays.
Applicable to studies of differentiation and APP modulation.
Supplied in small quantities for research applications.
Handle according to safety data sheet instructions.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More